Fetal DNA Chip (version 2.0)

Fetal DNA chip is a diagnostic platform that uses microarray technology to analyze fetal DNA. The fetal DNA chip's reliability and comprehensiveness make it a valuable tool in prenatal care, supporting informed decision-making for families.

Download Brochure
Menu

Test Introduction

Fetal DNA Chip V2 is a Chromosomal Microarray (CMA) test specifically designed to diagnose common Microdeletion/ duplication syndromes which would not be detected by conventional karyotype analysis. The version 2 chip now also enables us to diagnose uniparental isodisomy.

The Fetal DNA Chip testing was first launched in Hong Kong in 2009 by The Department of Obstetrics and Gynaecology of the Chinese University of Hong Kong.

Fetal Chip test has range of applications, including miscarriages, invasive prenatal diagnosis for high risk pregnancies such as fetal ultrasound anomalies and/or other indications.

What Fetal DNA Chip (version 2.0) covers

Benefits from this test:

  • More Comprehensive than Karyotyping: In addition to major chromosomal abnormalities, the Fetal DNA Chip can diagnose more than 100 recognized microdeletion/ duplication syndromes and uniparental isodisomy.
  • Higher Resolution: 50-fold higher and detects much smaller abnormalities than karyotyping analysis.
  • Rapid Result: Reporting time within 7-10 working days. The reporting for karyotyping analysis usually takes 2 to 3 weeks.

Medical treatment has to be individualised and can only be rendered after adequate assessment of your condition through appropriate clinical examination, and after discussion with your doctor. You should not rely on the information provided herein. Please note that the contents of this page are provided on the understanding that no surgical or medical advice or recommendation is being rendered.

How it Works

Patient Story

A Patient’s Journey: Invasive vs. Non-Invasive Testing

When Emily found out she was pregnant, joy quickly turned to worry. Her family history of genetic conditions made her pregnancy high-risk. She had initially heard about invasive testing, which involved needles and carried a risk of miscarriage. The thought of it filled Emily with dread and anxiety. Then, she learned about non-invasive prenatal testing (NIPT). A simple blood draw from her arm, no risk to her baby, and accurate results. Choosing NIPT allowed Emily to feel at ease, knowing she could monitor her baby’s health without the fear and stress of invasive procedures. When her results came back normal, the relief was immense, allowing her to enjoy her pregnancy with peace of mind.

Other Information

Fetal DNA Chip (version 2.0)

Who will benefit from this test?

  1. Fetal abnormalities revealed by ultrasound
    examination.
  2. Positive result of Down’s Syndrome Screening.
  3. Previous baby with congenital abnormalities.
  4. Couples with chromosomal abnormalities.
  5. Couples with previous miscarriage or stillbirth.
  6. Pregnant women undergoing invasive testing due
    to high-risk screening result.

Important notes for Fetal DNA Chip:

  1. Does not test for ALL genetic conditions: Unable to
    detect balanced translocations, inversions, low level
    mosaicism and point mutations.
  2. Normal test results do not exclude other genetic
    causes that are undetectable by Fetal DNA Chip V2.